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Using Obese Mouse Models in Research: Special Considerations for IACUC Members, Animal Care Technicians, and Researchers

Lab Animal volume 34, pages 30–37 (2005)Cite this article

Abstract

The mouse is the animal most commonly used to study the underlying causes of and treatments for obesity. The author reviews many of the issues that should be considered by all involved in research with mice expressing this phenotype, and describes some procedures exclusive to obesity research.

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Figure 1: Wire-grid hanging cages.
Figure 2: Core body temperature measurement in an obese mouse.
Figure 3: Running-wheel cages.

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Acknowledgements

The author would like to thank Christopher A. Coyle, Franc-Eric A. Wiedmer, and Hilary Woodcock for careful reading of the manuscript and helpful suggestions. This work was supported by grants from the US National Institutes of Health (R01 DK59903, R03 HD42499, and P30 DK46200).

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  1. The author is an Associate Professor in the Department of Veterinary and Animal Sciences, and IACUC Chair at the University of Massachusetts, Amherst, MA 01003.,

    Deborah J. Good PhD

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Correspondence to Deborah J. Good PhD.

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Good, D. Using Obese Mouse Models in Research: Special Considerations for IACUC Members, Animal Care Technicians, and Researchers. Lab Anim 34, 30–37 (2005). https://doi.org/10.1038/laban0205-30

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