Summary
The genetic variation of the human serum orosomucoid (ORM) was investigated by isoelectric focusing (IEF) followed by immunofixation in 15 different populations from East Midlands (United Kingdom), India, Sri Lanka, and Cambodia. Statistically significant differences were observed between various Asiatic and British populations, however differences within Asiatic and European populations were minor. The distribution ofORM1 alleles in populations investigated to date suggests an interesting east-west geographical cline. There is a suggestion that present day wide polymorphism at theORM1 locus may be influenced by selection.
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Mastana, S.S., Jayasekara, R., Fisher, P. et al. Genetic polymorphism of orosomucoid (ORM) in populations of the United Kingdom, Indian subcontinent, and Cambodia. Jap J Human Genet 38, 289–296 (1993). https://doi.org/10.1007/BF01874139
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DOI: https://doi.org/10.1007/BF01874139
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