Summary
The alpha-2-HS-glycoprotein (A2HS) polymorphism was studied in a Japanese population using polyacrylamide gel isoelectric focusing, followed by immunoblotting. Two new alleles, designatedA2HS *7 andA2HS *8, were observed.
Article PDF
References
Anderson, N.L. and Anderson, N.G. 1979. Microheterogeneity of serum transferrin, haptoglobin and α2HS glycoprotein examined by high resolution two-dimensional electrophoresis.Biochem. Biophys. Res. Commun. 88: 256–265.
Cox, D.W. and Andrews, B.J. 1983. Silver stain immunofixation for α2HS-glycoprotein: A new method for detection of protein heterogeneity. InElectrophoresis '82, Stathakos, D., ed., Walter de Gruyter, Berlin, pp. 243–247.
Cox, D.W., Andrews, B.J., and Wells, D. 1986. Genetic polymorphism of α2HS-glycoprotein.Am. J. Hum. Genet. 38: 699–706.
Ohya, I., Iwasa, M., Komoriya, H., and Bunnai, Y. 1985. α2HS-glycoprotein phenotypes in Gifu Prefecture.Res. Pract. Forens. Med. 28:5–8.
Umetsu, K., Kashimura, S., Ikeda, N., and Suzuki, T. 1984. A new α2HS-glycoprotein allele (AHS *5) in two Japanese families.Hum. Genet. 68: 264–265.
Umetsu, K., Yuasa, I., and Suzuki, T. 1986. The polymorphism of desialyzed α2HS-glycoprotein (AHS): isoelectric focusing in 2.5m urea as a method for identification of genetic variants.Hum. Genet. 73: 372–373.
Weidinger, S., Schwarzfisher, F., Burgemeister, R., and Cleve, H. 1984. Genetic alpha-2-HS glycoprotein phenotypes demonstrated by isoelectric focusing and immunofixation, InElectrophoresis '84, Neuhoff, V., ed., Verlag Chemie, Weinheim, pp. 487–490.
Weidinger, S. 1986. Isoelektrische Fokussierung und Print Immunfixation: ein schnelles Verfahren zur Typisierung des Alpha-2-HS-glykoproteins. InElektrophorese Forum '86, Radola, B.J., ed., Technische Universität München, Freising-Weihenstephan, pp. 156–162.
Yuasa, I., Taira, T., Suenaga, K., Ito, K., and Okada, K. 1985. Determination of α2HS-glycoprotein phenotypes by isoelectric focusing and immunoblotting: polymorphic occurence ofHSGA *5 in Okinawa.Hum. Genet. 70: 32–34.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Umetsu, K., Yuasa, I., Ikuta, M. et al. Alpha-2-HS-glycoprotein (A2HS) polymorphism in a Japanese population: Existence of two new variants. Jap J Human Genet 32, 263–266 (1987). https://doi.org/10.1007/BF01876882
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01876882