Summary
This paper reports a rare case of complex structural rearrangement involving four chromosomes. The patient, a five-year old girl, exhibits mild physical deformities, such as hypertelorism, blepharophimosis, brachydactyly and clinodactyly of both the second and fifth fingers. Using various banding techniques, the complicated multiple rearrangement could be interpreted as a unique combination of non-reciprocal translocation and insertion involving chromosomes 7, 10, 14 and 21.
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de Asis, M.L., Saito, F. & Tonomura, A. Complex structural rearrangement of chromosomes 7, 10, 14 and 21. Jap J Human Genet 29, 453–459 (1984). https://doi.org/10.1007/BF01876503
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DOI: https://doi.org/10.1007/BF01876503