Summary
Cycling populations of Aedes aegypti were set up in cages and managed in such a way that the populations had a maximum of threefold recovery potential in response to control measures. Into three such populations daily releases were made of males which had been chemosterilised, or were double translocation heterozygotes (T1T3) or T1T3 with sex ratio distortion (DT1T3). Eradication of the populations was achieved with all cases, but the rate of suppression was markedly slower with T1T3 than the other two systems, with which the rates were similar. T1T3 and DT1T3 releases introduced considerable inherited genetic loads into the target populations. The results were in general agreement with computer predictions.
Similar content being viewed by others
Article PDF
References
Craig, G B, and Hickey, W A. 1967. Genetics of Aedes aegypti. In Genetics of Insect Vectors of Disease, ed. J. W. Wright and R. Pal, pp. 67–128. Elsevier, Amsterdam.
Curtis, C F, Lorimer, N, Rai, K S, Suguna, S G, Uppal, D K, Kazmi, S J, Hallinan, E, and Dietz, K. 1975. Simulation of alternative genetic control systems for Aedes aegypti in outdoor cages and with a computer. WHO/VBG 75.516 (unpublished WHO document).
Curtis, C F, and Robinson, A S. 1971. Computer simulation of the use of double translocations for pest control. Genetics, 69, 92–113.
Fay, R W. 1964. The biology and bionomics of Aedes aegypti in the laboratory. Mosq News, 24, 300–308.
Fay, R W, and Elliason, D A. 1966. A preferred oviposition site as a surveillance method for Aedes aegypti. Mosq News, 26, 531–535.
Grover, K K, and Agarwal, H V. 1975. Studies on the chemosterilization of Aedes aegypti. 1. Evaluation of thiotepa as a sterilant in laboratory and field cages. WHO/VBG 75.558 (unpublished WHO document).
Grover, K K, and Sharma, V P. 1974. The present status of the work on induced sterility mechanisms for control of mosquitos Culex pipiens fatigans and Aedes aegypti at the WHO/ICMR Research Unit on Genetic Control of Mosquitos. J Com Dis, 6, 91–97.
Hickey, W A. 1970. Factors influencing distortion of sex ratio in Aedes aegypti. J med Entomol, 7, 727–735.
Hickey, W A, and Craig, G B. 1966a. Distortion of sex ratio in populations of Aedes aegypti. Can J Genet, and Cytol, 8, 260–278.
Hickey, W A, and Craig, G B. 1966b. Genetic distortion of sex ratio in the mosquito Aedes aegypti. Genetics, 53, 1177–1196.
Lorimer, N, Hallinan, E, and Rai, K S. 1972. Translocation homozygotes in the yellow fever mosquitos, Aedes aegypti. J Hered, 63, 159–166.
McDonald, P T, and Rai, K S. 1971. Population control potential of heterozygous translocations as determined by computer simulations. Bull Wld Hlth Org, 44, 829–845.
Rai, K S, Lorimer, N, and Hallinan, E. 1974. The present status of genetic methods for controlling Aedes aegypti. In The Use of Genetics in Insect Control, ed. R. Pal and M. Whitten pp. 119–132. Elsevier, Amsterdam.
Reuben, R, Panicker, K, Das, P K, Kazmi, S J, and Suguna, S G. 1975. A new paddle for the black jar ovitrap for surveillance of Aedes aegypti. WHO/VBC 75.548 (unpublished WHO document).
Singh, K R P, Brooks, G D, and Ansari, M A. 1974. Mass rearing of mosquitos. J Com Dis, 6, 121–126.
Singh, K R P, Razdan, R K, Vaidyanathan, V, and Malhotra, P R. 1975. Caging, marking and transportation of Culex pipiens fatigans for large scale genetic control operations. WHO/VBC 75.524 (unpublished WHO document).
Suguna, S G, and Curtis, C F. 1974. Sex ratio distorter strains in Aedes aegypti. J Com Dis, 6, 102–105.
Suguna, S G, Kazmi, S J, and Curtis, C F. 1975. Sex ratio distorter translocation homozygotes in Aedes aegypti. WHO/VBC 75.542 (unpublished WHO document).
Uppal, D K, Curtis, C F, and Rai, K S. 1974. A double translocation heterozygote in Aedes aegypti. J Com Dis, 6, 98–101.
White, G B. 1966. Chemosterilization of Aedes aegypti by pupal treatment. Nature, 210, 1372–1373.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Curtis, C., Grover, K., Suguna, S. et al. Comparative field cage tests of the population suppressing efficiency of three genetic control systems for Aedes aegypti. Heredity 36, 11–29 (1976). https://doi.org/10.1038/hdy.1976.2
Received:
Issue Date:
DOI: https://doi.org/10.1038/hdy.1976.2
This article is cited by
-
Establishment of a large semi-field system for experimental study of African malaria vector ecology and control in Tanzania
Malaria Journal (2008)
-
The genetic basis of resistance and sensitivity to the meiotic drive gene D in the mosquito Aedes aegypti L.
Genetica (1987)
-
Laboratory evalution of a translocation double heterozygote for genetic control of Aedes aegypti
Theoretical and Applied Genetics (1978)
-
Disorter-double translocation heterozygote systems in Aedes aegypti
Genetica (1977)
-
Sex ratio distorter-translocation homozygotes in Aedes aegypti
Genetica (1977)