Abstract
Modeling the expectations of detection rate for all birth defects based on characteristics of prenatal care delivery in California, the reported detection rates and the logistics and practicalities of testing lead to the conclusion that second trimester screening is preferable. Cost per birth defect detected is lowest and detection rates are comparable with second trimester screening using multiple serum markers as compared to ultrasound with or without serum markers in the first trimester.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Cunninqham, G., Currier, B. & Feuchtbaum, L. Impracticality and inefficiency of first trimester population screening for birth defects. Genet Med 2, 69 (2000). https://doi.org/10.1097/00125817-200001000-00072
Issue Date:
DOI: https://doi.org/10.1097/00125817-200001000-00072