Abstract
We have treated 26 retinal angiomas of less than 4.5mm in size in 15 eyes using repeated applications of contiguous argon blue green laser burns. All except one of the angiomas regressed without a massive exudative response of treatment. Haemorrhage occurred in two cases but only affected the visual outcome in one eye. Traction retinal detachment persisted in 50% of the large angiomas, despite regression of the tumour.
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References
von Hippel : E Über eine sehr seltene erkrankung der netzhaut. Arch f. Ophthalmol 1904; 59: 83–106.
Lindau A : Zür frage der angiomatosis retinae und ihrer hirnkompkationen. Acta Ophthalmol 1927; 4: 193–226.
van der Hoeve J : Eye symptoms In phakomatoses (The Doyne Memorial Lecture). Trans Ophlhalmol Soc UK 1932; 52: 380–410.
Seizinger BR, Rouleau GA, Ozelius LJ et al: von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma. Nature 1988: 332: 268–9.
Nicholson DH, Grccn WR, Kenyon KR : Light and electron microscopic study of early lesions in angiomatosis retinae. Am J Ophthalmol 1976; 82: 193–204.
Whitson IT . Welch RB, Green R : von Hippel-Lindau disease: case report of a patient with spontaneous regression of a retinal angioma. Retina 1986; 6: 253–9.
Jesberg JO . Spencer WH, Hoyt WF . Incipient lesions of von Hippel-Lindau disease. Arch Ophthalmol 1980; 80: 632–40.
Hardwig P . Robertson DM : von Hippel-Lindau disease: a familial, often lethal multi-system phakomatosis. Ophthalmology 1984; 91: 263–70.
Vail D : Angiomatosis retinae. cleven years after diathermy coagulation. Am J Ophthalmol 1958; 46: 525–34.
Holmes Sellors PJ, Archer D : The management of retinal angiomatosis. Trans Ophthalmol Soc UK 1969; 89: 529–43.
Annesley WH, Leonard BC, Shields JA, Tasman WS : Fifteen year review of treated cases of retinal angiomatosis. Trans Am Soc Otol Ophlhalmol 1977; 83: 446–53.
Sigelman J : Angiomatosis Retinae: chapter 12 in Retinal diseases. Pathogenesis, laser therapy and surgery. Little, Brown & Co. Boston/Toronto 1984: 311–30.
Wessing A : 10 jahre lichtkoagulation bei angiomatosis retinae. Klin Mbl Augenheilk 1967; 150: 57–71.
Goldberg MF, Koenig S : Argon laser treatment of von Hippel-Lindau retinal angiomas I. Clinical and angiographic findings. Arch Ophthalmol 1974; 92: 121–5.
Apple DJ, Goldberg MF, Wyhinny GJ : Argon laser treatment of von Hippel-Lindau retinal angiomas II. Histopathology of treated lesions. Arch Ophthalmol 1974; 92: 126–30.
Duke-Elder S : System of ophthalmology Vol. 10. Diseases of the retina. C. V. Mosby Co., St Louis 1967; 738–54.
Welch RB : von Hippel-Lindau disease: the recognition and treatment of early angiomatosis retinae and the use of cryotherapy as an adjunct to surgery. Trans Ophthalmol Soc 1970; 68: 367–424.
Nicholson DH, Green WR : Vascular tumours of the retina and optic nerve. Chapter 5 in Paediatric ocular tumours, Masson Publishing USA Inc 1981: 65–73.
Gass, JDM : Angiomatosis retinae (von Hippel's disease). Chapter 10 in Differential diagnosis of intraocular tumours. A stereoscopic presentation. C.V. Mosby Co., St Louis 1974.
Machemer R : Pathogenesis and classification of massive periretinal proliferation. Br J Ophthalmol 1978; 62: 737–47.
Plowman PN, Harnett AN : Radiotherapy in benign orbital disease. I: Complicated ocular angiomas. Br J Ophthalmol 1988; 72: 286–8.
Gass JD, Braunstein R : Sessile and exophytic capillary angiomas of the juxtapapillary retina and optic nerve head. Arch Ophthmol 1980; 98: 1790–7.
Nicholson DH, Anderson LS, Blodi C : Rhegmatogenous retinal detachment in angiomatosis retinae. Am J Ophthalmol 1986; 101: 187–9.
Huson SM, Harper PS, Hourihan MD, Cole G, Weeks RD, Compston DAS : Cerebellar haemangioblastoma and von Hippel-Lindau disease. Brain 1986; 109: 1297–310.
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Lane, C., Turner, G., Gregor, Z. et al. Laser treatment of retinal angiomatosis. Eye 3, 33–38 (1989). https://doi.org/10.1038/eye.1989.5
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DOI: https://doi.org/10.1038/eye.1989.5
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