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Disseminated Scopulariopsis brevicaulis infection in an allogeneic stem cell recipient

Bone Marrow Transplantation volume 46, pages 1276–1277 (2011)Cite this article

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In patients with hematological diseases complicated by neutropenia, Candida and Aspergillus infections are commonly described. However, over the last few years, opportunistic infections due to multi-resistant fungi have been increasingly reported. We describe here a fatal case of disseminated Scopulariopsis brevicaulis infection in an allogenic stem cell recipient.

In January 2007, a 43-year-old woman was diagnosed with myelodysplasia. In March 2008, she developed secondary AML. In July 2008, induction chemotherapy with a classical 3+7 regimen failed to induce CR and a second induction course of chemotherapy induction was administered with anthracycline and high-dose cytarabine. The chemotherapy resulted in a prolonged period of profound neutropenia.

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Acknowledgements

We thank F Dromer et al. (centre Nation de Référence de la Mycologie et des antifongiques) for confirmation of our Etest results by EUCAST susceptibility testing.

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Authors and Affiliations

  1. Department of Infectious Diseases, Cochin Hospital, Université Paris Descartes, Assistance Publique Hôpitaux de Paris, Paris, France

    M Vignon, D Michonneau & D Salmon

  2. Department of Parasitology-Mycology, Cochin Hospital, Université Paris Descartes, Assistance Publique Hôpitaux de Paris, Paris, France

    M-T Baixench & A Paugam

  3. Department of Hematology, Cochin Hospital, Université Paris Descartes, Assistance Publique Hôpitaux de Paris, Paris, France

    C Al-Nawakil & D Bouscary

  4. Department of Hematology, Necker Hospital, Université Paris Descartes, Assistance Publique Hôpitaux de Paris, Paris, France

    A Buzyn

Authors
  1. M Vignon
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  2. D Michonneau
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  3. M-T Baixench
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  4. C Al-Nawakil
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  5. D Bouscary
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  7. D Salmon
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  8. A Paugam
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Correspondence to A Paugam.

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Vignon, M., Michonneau, D., Baixench, MT. et al. Disseminated Scopulariopsis brevicaulis infection in an allogeneic stem cell recipient. Bone Marrow Transplant 46, 1276–1277 (2011). https://doi.org/10.1038/bmt.2010.292

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