Abstract
We analysed determinants of risk of cervical cancer in women aged less than 45 years using data from a case-control study conducted in Italy. Cases were 261 women aged < 45 years with histologically confirmed invasive cervical cancer. Controls were 257 women aged < 45 years, with acute, non-neoplastic conditions, judged to be unrelated to any of the known or suspected risk factors for cervical cancer. In comparison with women reporting one or no sexual partner, the multivariate odds ratio (OR) of cervical cancer was 2.4 (95% confidence interval, CI, 1.3-4.6), for women reporting two or more sexual partners, and, in comparison with women reporting their first intercourse at 17 years of age or before, the multivariate OR was 0.5 (95% CI 0.3-0.9) in women aged > or =23 years at first intercourse. The risk of cervical cancer was higher in parous women and increased with number of births (OR = 8.1 for three or more births). Among parous women the risk tended to increase with later age at last birth; in comparison with parous women reporting their last birth before age 25, the OR was 1.9 in those reporting their last birth at > or =35 years. No clear association emerged between oral contraceptive use, smoking, education, social class and risk of cervical cancer.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 24 print issues and online access
$259.00 per year
only $10.79 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Parazzini, F., Chatenoud, L., La Vecchia, C. et al. Determinants of risk of invasive cervical cancer in young women. Br J Cancer 77, 838–841 (1998). https://doi.org/10.1038/bjc.1998.136
Issue Date:
DOI: https://doi.org/10.1038/bjc.1998.136
This article is cited by
-
LEEP Verses Cryotherapy in CIN
The Journal of Obstetrics and Gynecology of India (2011)
-
Human papillomavirus infection: an Anonymous Prevalence Study in South Wales, UK
British Journal of Cancer (2006)
-
A population-based study on the risk of cervical cancer and cervical intraepithelial neoplasia among grand multiparous women in Finland
British Journal of Cancer (2004)