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  • Clinical Oncology
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The influence of ifosfamide scheduling on acute nephrotoxicity in children

British Journal of Cancer volume 75, pages 1356–1359 (1997)Cite this article

Abstract

Nephrotoxicity is a significant problem in children after treatment with ifosfamide. Acute changes in renal function were compared in 16 children receiving 9 g m(-2) of ifosfamide as a 72-h continuous infusion on one occasion and, on another course, divided into three 1-h infusions on consecutive days. Subclinical acute nephrotoxicity was demonstrated with both schedules, but there were no significant differences in severity.

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Authors and Affiliations

  1. Sir James Spence Institute of Child Health, The Royal Victoria Infirmary, Newcastle upon Tyne, UK

    MW English

Authors
  1. MW English
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  2. R Skinner
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  3. ADJ Pearson
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  4. L Price
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  5. R Wyllie
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  6. AW Craft
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English, M., Skinner, R., Pearson, A. et al. The influence of ifosfamide scheduling on acute nephrotoxicity in children. Br J Cancer 75, 1356–1359 (1997). https://doi.org/10.1038/bjc.1997.229

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  • DOI: https://doi.org/10.1038/bjc.1997.229

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