Abstract
Thymectomy effectively prevents the development of spontaneous lymphoma in the AKR but how this effect is achieved remains to be determined. One possible mechanism, namely suppression of genomic expression of the oncogenic murine leukaemia virus now seems unlikely since levels of the group specific MuLV antigen were in comparision with their sham operated controls unaltered in both neonatally and adult thymectomized AKR.
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Tuffrey, M., Crewe, P., Dawson, L. et al. Murine leukaemia virus expression in the AKR following thymectomy. Br J Cancer 32, 465–470 (1975). https://doi.org/10.1038/bjc.1975.248
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DOI: https://doi.org/10.1038/bjc.1975.248
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