Abstract
The methylated purine content of tRNA bulk extracted from human hepatomata has been compared with that in normal human liver. The analyses were carried out with the aid of ion-exchange chromatography. The molar proportions of 5 bases detected in acid hydrolysates of tumour tRNA (N2-methylguanine, 1-methylguanine, 7-methylguanine, N2-dimethylguanine and 1-methyladenine) were not abnormally elevated.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 24 print issues and online access
$259.00 per year
only $10.79 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Rights and permissions
About this article
Cite this article
Ho, Y., Lin, H. On the Methylated Purine Content of tRNA Present in Tumours. Br J Cancer 29, 324–327 (1974). https://doi.org/10.1038/bjc.1974.74
Issue Date:
DOI: https://doi.org/10.1038/bjc.1974.74