Abstract
Seventy-five cases of malignant solid tumours treated by a quadruple chemotherapy regime are described. These tumours originated in the breast, head and neck, bronchus, genital tract, cutaneous melanoma, soft tissue and gastro-intestinal tract. All 14 patients with breast carcinoma underwent remission and in 6 this was complete. Significant remissions were seen in gastro-intestinal and head and neck malignancies, and also in the soft tissue group. A short response was noted in 6 of 14 cases of bronchial carcinoma. Malignant melanoma, testicular, ovarian and cervical carcinomata failed to respond.
In all, 40 of 75 patients underwent objective remission.
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Hanham, I., Newton, K. & Westbury, G. Seventy-Five Cases of Solid Tumours Treated by a Modified Quadruple Chemotherapy Regime. Br J Cancer 25, 462–478 (1971). https://doi.org/10.1038/bjc.1971.59
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DOI: https://doi.org/10.1038/bjc.1971.59
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