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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Severe hemolytic disease of the newborn from anti-e

Journal of Perinatology volume 28, pages 230–232 (2008)Cite this article

Abstract

Maternal antibody-mediated fetal red blood cell destruction secondary to non-D Rhesus (Rh) antibodies is a significant cause of hemolytic disease of the newborn (HDN). Here, we report a rare case of severe HDN associated with maternal antibody to Rh e. In addition to severe anemia, the infant developed thrombocytopenia, conjugated hyperbilirubinemia and cholelithiasis. Resolution of the infant's cholelithiasis occurred following treatment with ursodeoxycholic acid.

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Authors and Affiliations

  1. Department of Neonatology, US Naval Hospital Okinawa and 18th Medical Group, Kadena Air Base, Kadena, Japan,

    R M McAdams, S A Dotzler, L W Winter & J D Kerecman

Authors
  1. R M McAdams
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  2. S A Dotzler
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  3. L W Winter
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  4. J D Kerecman
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Corresponding author

Correspondence to R M McAdams.

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The opinions expressed in this paper are solely those of the authors and do not represent the views of the United States Air Force, the United States Navy, the Department of Defense or the United States Government.

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McAdams, R., Dotzler, S., Winter, L. et al. Severe hemolytic disease of the newborn from anti-e. J Perinatol 28, 230–232 (2008). https://doi.org/10.1038/sj.jp.7211897

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