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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Endogenous group B streptococcal endophthalmitis in a preterm infant

Abstract

Endogenous endophthalmitis is a rare complication of bacteremia. Proper intervention is critical, as the majority of affected patients lose vision in the infected eye. Treatment options include systemic antibiotics, intravitreous antibiotics and vitrectomy. We report a case of endogenous endophthalmitis presenting as leukocoria in a premature neonate with group B streptococcal meningitis.

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References

  1. Jackson TL, Eykyn SJ, Graham EM, Stanford MR . Endogenous bacterial endophthalmitis: a 17-year prospective series and review of 267 reported cases. Surv Opthalmol 2003; 48: 403–423.

    Article  Google Scholar 

  2. Greene GR, Carroll WL, Morozumi PA, Ching FC . Endophthalmitis associated with group-B streptococcal meningitis in an infant. Am J Dis Child 1979; 133: 752–753.

    CAS  PubMed  Google Scholar 

  3. Berger BB . Endophthalmitis complicating neonatal group B streptococcal septicemia. Am J Ophthalmol 1982; 92: 681–684.

    Article  Google Scholar 

  4. Greenwald MJ, Wohl LG, Sell CH . Metastatic bacterial endophthalmitis. A contemporary reappraisal. Surv Ophthalmol 1986; 31: 81–101.

    Article  CAS  Google Scholar 

  5. Wu Z, Uzcategui N, Chung M, Song J, Lim JI . Group B streptococcal endogenous endophthalmitis in a neonate. Retina 2006; 26: 472–473.

    PubMed  Google Scholar 

  6. Lin FY, Weismann LE, Troendle J, Adams K . Prematurity is the major risk factor for late-onset group B streptococcus disease. J Infect Dis 2003; 188: 267–271.

    Article  Google Scholar 

  7. Bottoli I, Beharry K, Modanlou HD, Norris K, Ling E, Noya F et al. Effect of group B streptococcal meningitis on retinal blood and choroidal blood flow in newborn pigs. Invest Ophtalmol Vis Sci 1995; 36: 1231–1239.

    CAS  Google Scholar 

  8. Matasova K, Hudecova J, Zibolen M . Bilateral endogenous endophthalmitis as a complication of late-onset sepsis in a premature infant. Eur J Pediatr 2003; 162: 346–347.

    PubMed  Google Scholar 

  9. Donahue SP, Kowalski RP, Jewart BH, Friberg TR . Vitreous cultures in suspected endophthalmitis. Biopsy or vitrectomy? Ophthalmology 1993; 100: 452–455.

    Article  CAS  Google Scholar 

  10. Okhravi N, Adamson P, Carroll N, Dunlop A, Matheson MM, Towler HMA et al. PCR-based evidence of bacterial involvement in eyes with suspected intraocular infection. Invest Ophthalmol Vis Sci 2000; 41: 3474–3479.

    CAS  PubMed  Google Scholar 

  11. Okhravi N, Adamson P, Matheson MM, Towler HM, Lightman S . PCR-RFLP-mediated detection and speciation of bacterial sepsis causing endophthalmitis. Invest Ophthalmol Vis Sci 2000; 41: 1438–1447.

    CAS  PubMed  Google Scholar 

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Acknowledgements

We thank Dr William Walsh for review of this paper and helpful discussion.

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Correspondence to J-H Weitkamp.

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Sparks, J., Recchia, F. & Weitkamp, JH. Endogenous group B streptococcal endophthalmitis in a preterm infant. J Perinatol 27, 392–394 (2007). https://doi.org/10.1038/sj.jp.7211685

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