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Evidence vs Experience in Neonatal Practice

Journal of Perinatology volume 25, page S1 (2005)Cite this article

Over the past 25 years, significant progress has been made in the care of extremely premature infants. The discovery of surfactant replacement, importance of thermal regulation, better ventilatory management, antenatal steroid treatment, control of infection and several other interventions have decreased perinatal mortality and morbidity significantly. However, the incidence of prematurity has not decreased and clinicians are still faced with the challenge of caring for extremely premature infants and their associated morbidities.

As the practice of perinatal medicine continues to move toward an evidence-based approach, we are faced with the lack of randomized clinical trials for many routinely practiced interventions. For example, optimal ventilation strategy for respiratory failure, oxygen saturation ranges, blood pressure, nutrition, etc. are still not clearly known for extremely premature infants. This quandary exists despite the significant improvements in technology in the neonatal intensive care unit in recent years.

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  1. Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA

    Kris Sekar MD

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  1. Kris Sekar MD
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2004 Evidence vs Experience Conference Chair.

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Sekar, K. Evidence vs Experience in Neonatal Practice. J Perinatol 25 (Suppl 2), S1 (2005). https://doi.org/10.1038/sj.jp.7211307

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