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Continuous Blood Gas Monitoring Using an In-Dwelling Optode Method: Clinical Evaluation of the Neotrend Sensor Using a Luer Stub Adaptor to Access the Umbilical Artery Catheter

Journal of Perinatology volume 22, pages 367–369 (2002)Cite this article

Abstract

INTRODUCTION: Arterial blood gases are essential in the management of critically ill neonates. A new technology using the Neotrend system (Diametrics Medical) allows for continuous measurement of pH, PaCO2, and PaO2, and calculates oxygen saturation, bicarbonate, and base excess.

OBJECTIVE: To evaluate and compare the results of continuous blood gas measurement using the Neotrend system with a standard system of blood gas analysis in our intensive care unit.

DESIGN: Prospective, controlled, interventional study.

SETTING: The neonatal intensive care unit of a tertiary referral center.

PATIENTS: Neonates with respiratory distress who required respiratory support and frequent arterial blood gas sampling and had a UAC.

RESEARCH DESIGN AND METHOD: To enable Neotrend sensor access to an existing Argyle umbilical artery catheter (UAC) the catheter was cut at the 25-cm mark and connected to an 18-gauge blunt needle luer stub adaptor (Vygon 95440). The study began with the insertion of the Neotrend sensor. Subjects remained on the study until the UAC was discontinued and/or frequent blood gases were no longer needed. The blood gas results from the Neotrend system were not used in clinical management of the patient.

BLOOD GAS MEASUREMENT: During the study period, with each blood sample drawn for laboratory analysis, a printout from the Neotrend monitor was recorded for comparison.

RESULTS: A total of 217 pairs of blood gas samples were collected from seven neonates. The mean bias/precision for pH was 0.01/0.04; for PaO2 0.72/18.5 mm Hg; and for PaCO2 3.96/2.63 mm Hg. The correlation (r value) between the sensor reading and the blood gases were 0.85 for pH, 0.96 for PaO2, and 0.92 for PaCO2.

CONCLUSION: The blood gases compared in the two methods had a strong correlation for pH, PaCO2, PaO2, and oxygen saturation. Although the bicarbonate and base excess values showed suboptimal statistical correlation, the difference was not clinically relevant. Results of this study indicate that this technology provides an accurate means of monitoring continuous blood gas parameters in neonatal patients. It also allows reduced healthcare provider exposure to blood and decreased patient iatrogenic blood loss.

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Authors and Affiliations

  1. Department of Neonatology, Children's National Medical Center and The George Washington University School of Medicine, Washington, DC, USA

    K Rais-Bahrami MD, Gerald T Mikesell BS, CCP & Billie L Short MD

  2. Department of Biomedical Engineering, Children's National Medical Center and The George Washington University School of Medicine, Washington, DC, USA

    Oswaldo Rivera

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  1. K Rais-Bahrami MD
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  2. Oswaldo Rivera
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  3. Gerald T Mikesell BS, CCP
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  4. Billie L Short MD
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Rais-Bahrami, K., Rivera, O., Mikesell, G. et al. Continuous Blood Gas Monitoring Using an In-Dwelling Optode Method: Clinical Evaluation of the Neotrend Sensor Using a Luer Stub Adaptor to Access the Umbilical Artery Catheter. J Perinatol 22, 367–369 (2002). https://doi.org/10.1038/sj.jp.7210735

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