Abstract
Proteolysis-inducing factor (PIF), a novel cachectic factor, is detectable in the urine of cancer patients experiencing weight loss. We report the expression of PIF in gastrointestinal cancers, and a correlation between PIF expression in tumours, its detection in urine and weight-loss. These data provide the first direct evidence that tumours are the source of PIF in humans. © 2001 Cancer Research Campaign http://www.bjcancer.com
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Cabal-Manzano, R., Bhargava, P., Torres-Duarte, A. et al. Proteolysis-inducing factor is expressed in tumours of patients with gastrointestinal cancers and correlates with weight loss. Br J Cancer 84, 1599–1601 (2001). https://doi.org/10.1054/bjoc.2001.1830
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DOI: https://doi.org/10.1054/bjoc.2001.1830
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