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Safe administration of etoposide phosphate after hypersensitivity reaction to intravenous etoposide

Abstract

Etoposide is commonly used in a variety of malignancies. A well known but rare toxicity are hypersensitivity reactions, usually manifested by chest discomfort, dyspnoea, bronchospasm and hypotension. We report the details of a patient who developed hypersensitivity reactions to intravenous etoposide, but subsequently tolerated the administration of intravenous etoposide phosphate with no sequalae.

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Correspondence to J Siderov.

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Siderov, J., Prasad, P., De Boer, R. et al. Safe administration of etoposide phosphate after hypersensitivity reaction to intravenous etoposide. Br J Cancer 86, 12–13 (2002). https://doi.org/10.1038/sj.bjc.6600003

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