Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Brief Communication
  • Published:

A polymorphic microsatellite marker in the human p55 TNF receptor, CD120a

Genes & Immunity volume 1, pages 228–230 (2000)Cite this article

Abstract

We provide characterization of a highly polymorphic dinucleotide repeat in the human TNF-receptor 1 gene (TNFR1, TNFRp55, CD120a). We have observed 11 alleles at this locus in individuals from the West of Scotland. In a panel of healthy, unrelated individuals from the West of Scotland (n = 143), the overall heterozygosity was 68% , indicating the potential usefulness of these markers in immunogenetic studies.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

Author information

Author notes

  1. J Eskdale: JE is supported in part by the Breast Cancer Campaign. This project has been funded in whole or in part with US Federal funds from the National Cancer Institute, National Institutes of Health (contract NO1-CO-56000). The contents of this publication do not necessarily reflect the view or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. Government. The publisher or recipient acknowledges right of the US Government to retain a nonexclusive, royalty-free license in and to any copyright covering the article.

Authors and Affiliations

  1. University of Glasgow Department of Surgery, Queen Elizabeth Building, Glasgow Royal Infirmary, Glasgow, G31 2ER, Scotland

    J Eskdale, C Armstrong & G Gallagher

  2. Laboratory of Molecular Immunology, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 117984 and Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, 119899, Russia

    RL Turestkaya, DV Kuprash & SA Nedospasov

  3. Division of Basic Sciences, Intramural Research Support Program SAIC Frederick and Laboratory of Molecular Immunoregulation, National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, 21702, MD, USA

    DV Kuprash & SA Nedospasov

Authors
  1. J Eskdale
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. RL Turestkaya
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C Armstrong
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. DV Kuprash
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. SA Nedospasov
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. G Gallagher
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to SA Nedospasov or G Gallagher.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Eskdale, J., Turestkaya, R., Armstrong, C. et al. A polymorphic microsatellite marker in the human p55 TNF receptor, CD120a. Genes Immun 1, 228–230 (2000). https://doi.org/10.1038/sj.gene.6363663

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.gene.6363663

Keywords

This article is cited by

Search

Advanced search

Quick links