A crystal structure reveals how a protein kinase is activated by the binding of a small molecule at a pocket far from the catalytic site. This opens the door to the design of modulators of protein phosphorylation.
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Liu, Y. Caught in the activation. Nature 461, 484–485 (2009). https://doi.org/10.1038/461484a
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DOI: https://doi.org/10.1038/461484a