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Physiology

Keeping it regular with protons

Muscle coordination is mostly governed by motor programs built into the nervous system. But one program — the defecation cycle in a worm — has a mechanism that avoids nerves completely and uses protons as signals.

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Figure 1: Proton concentrations and worm defecation.
Figure 2: Communication between cells in a worm's defecation cycle.

References

  1. Beg, A. A., Ernstrom, G. G., Nix, P., Davis, M. W. & Jorgensen, E. M. Cell 132, 149–160 (2008).

    Article  CAS  Google Scholar 

  2. Pfeiffer, J., Johnson, D. & Nehrke, K. Curr. Biol. 18, 297–302 (2008).

    Article  CAS  Google Scholar 

  3. Branicky, R. & Hekimi, S. Trends Genet. 22, 571–579 (2006).

    Article  CAS  Google Scholar 

  4. Dal Santo, P., Logan, M. A., Chisholm, A. D. & Jorgensen, E. M. Cell 98, 757–767 (1999).

    Article  CAS  Google Scholar 

  5. Take-Uchi, M. et al. Proc. Natl Acad. Sci. USA 95, 11775–11780 (1998).

    Article  ADS  CAS  Google Scholar 

  6. Barnstable, C. J. Curr. Opin. Neurobiol. 3, 520–525 (1993).

    Article  CAS  Google Scholar 

  7. Krishtal, O. A., Osipchuk, Y. V., Shelest, T. N. & Smirnoff, S. V. Brain Res. 436, 352–356 (1987).

    Article  CAS  Google Scholar 

  8. Lingueglia, E. J. Biol. Chem. 282, 17325–17329 (2007).

    Article  CAS  Google Scholar 

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Prolo, L., Goodman, M. Keeping it regular with protons. Nature 452, 35–36 (2008). https://doi.org/10.1038/452035a

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