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Docetaxel-induced Meibomian duct inflammation and blockage leading to chalazion formation

Abstract

We report a 71-year male with castration-resistant metastatic prostate cancer who was treated with weekly docetaxel for 12 weeks and developed significant eye irritation and dryness during treatment. Subsequently, the patient presented with a lower eyelid mass, which on excision was demonstrated to be a chalazion. Docetaxel induced Meibomian duct inflammation and blockage is the likely cause of this presentation in a patient with no history of eyelid masses in the past.

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Correspondence to D L Trump.

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Gupta, S., Silliman, C. & Trump, D. Docetaxel-induced Meibomian duct inflammation and blockage leading to chalazion formation. Prostate Cancer Prostatic Dis 10, 396–397 (2007). https://doi.org/10.1038/sj.pcan.4500939

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