Abstract
Current opinion advocates the use of nephrostomies in hormone naive patients with obstructive uropathy while hormone resistant patients require an individual approach. Patients undergoing a nephrostomy for uropathy were retrospectively analysed, with particular interest in hormone status and blood levels. Over a 46-month period, 26/112 nephrostomies were performed for prostate cancer induced uropathy. Survival was 226.5 days for hormone naive patients, 114.3 days in the responsive group and 100.2 days if resistant. Bilateral cases survived 72.1 days versus 157.6 days for unilateral patients. All patients should be considered for nephrostomy despite their hormone status.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 4 print issues and online access
$259.00 per year
only $64.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Paul AB, Love C, Chisholm GD . The management of bilateral ureteric obstruction and renal failure in advanced prostate cancer. Br J Urol 1994; 74: 642–645.
Markowitz DM, Wong KT, Laffey KJ, Bixon R, Nagler HM, Martin EC . Maintaining quality of life after palliative diversion for malignant ureteral obstruction. Urol Radiol 1989; 11: 129–132.
Colombel M, Mallame W, Abbou CC . Influence of urological complications on the prognosis of prostate cancer. Eur Urol 1997; 31: 21–24.
BAUS. Guidelines for the Management of Metastatic Prostate Cancer 2005.
Dowling RA, Carrasco CH, Babaian RJ . Percutaneous urinary diversion in patients with hormone-refractory prostate cancer. Urology 1991; 37: 89–91.
Hamdy FC, Williams JL . Use of dexamethasone for ureteric obstruction on advanced prostate cancer: percutaneous nephrostomies can be avoided. Br J Urol 1995; 75: 782–785.
Lau MW, Temperley DE, Mehta S, Johnson RJ, Barnard RJ, Clarke NW . Urinary tract obstruction and nephrostomy drainage in pelvic malignant disease. Urol 1995; 76: 565–569.
Van Dyke AH, Van Nagell JR . The prognostic significance of ureteral obstruction in patients with recurrent carcinoma of the cervix uteri. Surg Gynaecol Obstetr 1975; 141: 371–373.
Chiou RK, Chang WY, Horan JJ . Ureteral obstruction associated with prostate cancer: the outcome after percutaneous nephrostomy. J Urol 1990; 143: 957–959.
Fallon B, Olney L, Culp DA . Nephrostomy in cancer patients: to do or not to do? Br J Urol 1980; 52: 237–242.
Sandhu DP, Mayor PE, Sambrook PA, George NJ . Outcome and prognostic factors in patients with advanced prostate cancer and obstructive uropathy. Br J Urol 1992; 70: 412–416.
Acknowledgements
We would like to thank the radiology department for their expertise and assistance.
Author information
Authors and Affiliations
Corresponding author
Additional information
The authors confirm that this is an original piece of work that has not been submitted for publication elsewhere. As a retrospective study, no ethical permission or patient consent was obtained. Patient confidentiality has been protected.
Rights and permissions
About this article
Cite this article
Harris, M., Speakman, M. Nephrostomies in obstructive uropathy; how should hormone resistant prostate cancer patients be managed and can we predict who will benefit?. Prostate Cancer Prostatic Dis 9, 42–44 (2006). https://doi.org/10.1038/sj.pcan.4500858
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.pcan.4500858
Keywords
This article is cited by
-
Managing the local complications of locally advanced prostate cancer
Current Prostate Reports (2008)
-
Managing the local complications of locally advanced prostate cancer
Current Urology Reports (2007)
-
Urologische Aspekte in der Palliativmedizin
Der Onkologe (2007)
-
Palliative und supportive Therapie bei Patienten mit fortgeschrittenem Prostatakarzinom
Der Urologe (2007)