Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Paper
  • Published:

Home and office uroflowmetry for evaluation of LUTS from benign prostatic enlargement

Prostate Cancer and Prostatic Diseases volume 8, pages 45–49 (2005)Cite this article

Abstract

A group of 107 patients with lower urinary tract symptoms (LUTS) from benign prostatic enlargement (BPE) participated to the HOUSE Study (Home and Office Uroflowmetry Specific Evaluation). Patients received routine investigation, consisting of medical history taking, physical examination including digital rectal examination, prostate-specific antigen (PSA), assessment of symptoms listed both on the International Prostate Symptom Score and on ICS-male questionnaire. We examined the results of uroflowmetry evaluation in this population; data were analysed to observe if any circadian changes of parameters obtained with home uroflowmetry could be detected. We searched a correlation between Qmax, Qave and ICS-benign prostatic hyperplasia symptom score: a significantly inverse correlation was found only for Qmax, confirming Qmax as a reliable parameter to quantify subjective symptoms. When examining the multiple flow curves recorded in the same patient with home uroflowmetry, voided volume and flow time had usually higher values during night-time: the existence of circadian changes of uroflowmetry parameters in patients with LUTS from BPE was confirmed, and lower values of average and maximum flow rates during sleep hours were recorded in the same patient. In conclusion, when evaluating the natural history or treatment outcome of individual patients or group of patients in clinical trials for evaluation of BPE and LUTS, an assessment including multiple measurements may be useful and of value.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1

Similar content being viewed by others

References

  1. De la Rosette JJMCH et al. Improved reliability of uroflowmetry investigations: results of a portable home-based uroflowmetry study. Br J Urol 1996; 78: 385–390.

    Article  CAS  Google Scholar 

  2. Ezz el Din K et al. The correlation between bladder outlet obstruction and lower urinary tract symptoms as measured by the International Prostate Symptoms Score. J Urol 1996; 156: 1020–1025.

    Article  Google Scholar 

  3. Golomb J et al. Variability and circadian changes in home uroflowmetry in patients with benign prostatic hyperplasia compared to normal controls. J Urol 1992; 147: 1044–1047.

    Article  CAS  Google Scholar 

  4. Boci R et al. Home uroflowmetry: improved accuracy in outflow assessment. Neurourol Urodyn 1999; 18: 25–32.

    Article  CAS  Google Scholar 

  5. Donovan JL et al. The ICS-BPH Study: the psychometric validity and reliability of the ICSmale questionnaire. Br J Urol 1996; 77: 554–562.

    Article  CAS  Google Scholar 

  6. Siroky MB, Olsson CA, Krane RJ . The flow rate nomogram: I. Development. J Urol 1979; 122: 665–668.

    Article  CAS  Google Scholar 

  7. Schäfer W . Analysis of bladder-outlet function with the linearized passive urethral resistance relation, linPURR, and a disease-specific approach for grading obstruction: from complex to simple. World J Urol 1995; 13: 47–58.

    Article  Google Scholar 

  8. Meier AHP et al. Reliability of free uroflowmetry using repeated measurements of homeflowmetry in males. Neurourol Urodyn 1994; 13: 453–454.

    Google Scholar 

  9. Sonke GS et al. Low reproducibility of maximum urinary flow rate determined by portable flowmetry. Neurourol Urodyn 1999; 18: 183–191.

    Article  CAS  Google Scholar 

  10. Blanker MH et al. Normal values and determinants of circadian urine production in older men: a population based study. J Urol 2002; 168 (4, Part1): 1453–1457.

    Article  CAS  Google Scholar 

  11. Porru D et al. Urinary symptoms in women with gynaecologic disorders: the role of symptom evaluation and home uroflowmetry. Arch Esp Urol 1998; 51: 843–848.

    CAS  PubMed  Google Scholar 

  12. Bosch JL et al. The International Prostate Symptom Score in a community-based sample of men between 55 and 74 years of age: prevalence and correlation of symptoms with age, prostate volume, flow rate and residual urine volume. Br J Urol 1995; 75: 622–630.

    Article  CAS  Google Scholar 

  13. Larosa M et al. Uroflowmetry in the assessment of patients with benign prostatic hyperplasia in Italian men. Acta Biomed Ateneo Parmense 1999; 64: 17–22.

    Google Scholar 

  14. Jensen KM et al. Some clinical aspects of uroflowmetry in elderly males. A population survey. Scand J Urol Nephrol 1986; 20: 93–99.

    Article  CAS  Google Scholar 

  15. Porru D et al. Relationship of flow rate with symptoms, quality of life and other clinical parameters in patients with LUTS suggestive of BPH. Eur Urol 2001; 40 (Suppl 1): 23–27.

    Article  Google Scholar 

  16. Blanker MH et al. Voided volumes: normal values and relation to lower urinary tract symptoms in elderly men, a community-based study. Urology 2001; 57: 1093–1098.

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by an educational grant from Boehringer Ingelheim, Milan, Italy.

Author information

Authors and Affiliations

  1. Divisione Urologia, IRCCS Policlinico S. Matteo, Pavia, Italy

    D Porru

  2. Azienda Ospedaliera S. Luigi di Orbassano, Università di Torino, Italy

    R M Scarpa

  3. Università Federico II, Napoli, Italy

    D Prezioso

  4. Università di Bologna, Italy

    A Bertaccini

  5. Boehringer Ingelheim Italia, Milano, Italy

    C A Rizzi

Authors
  1. D Porru
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R M Scarpa
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. D Prezioso
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A Bertaccini
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. C A Rizzi
    View author publications

    You can also search for this author in PubMed Google Scholar

Consortia

for HOUSE Study Group

Corresponding author

Correspondence to D Porru.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Porru, D., Scarpa, R., Prezioso, D. et al. Home and office uroflowmetry for evaluation of LUTS from benign prostatic enlargement. Prostate Cancer Prostatic Dis 8, 45–49 (2005). https://doi.org/10.1038/sj.pcan.4500763

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.pcan.4500763

Keywords

This article is cited by

Search

Advanced search

Quick links