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Developmental biology

A twist in a mouse tale

Studies of the retinoblastoma gene can still deliver surprises, and enlightenment. Several of the abnormalities in mice lacking this gene are, it seems, the indirect consequence of a placental defect.

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References

  1. Wu, L. et al. Nature 421, 942–947 (2003).

    Article  ADS  CAS  Google Scholar 

  2. Lee, E. Y.-H. P. et al. Nature 359, 288–294 (1992).

    Article  ADS  CAS  Google Scholar 

  3. Jacks, T. et al. Nature 359, 295–300 (1992).

    Article  ADS  CAS  Google Scholar 

  4. Clarke, A. R. et al. Nature 359, 328–330 (1992).

    Article  ADS  CAS  Google Scholar 

  5. Rossant, J. & Cross, J. C. Nature Rev. Genet. 2, 538–548 (2001).

    Article  CAS  Google Scholar 

  6. Williams, B. O. et al. EMBO J. 13, 4251–4259 (1994).

    Article  CAS  Google Scholar 

  7. Maandag, E. C. et al. EMBO J. 13, 4260–4268 (1994).

    Article  CAS  Google Scholar 

  8. Tsai, K. Y. et al. Mol. Cell 2, 293–304 (1998).

    Article  CAS  Google Scholar 

  9. Ziebold, U., Reza, T., Caron, A. & Lees, J. A. Genes Dev. 15, 386–391 (2001).

    Article  CAS  Google Scholar 

  10. Lasorella, A., Noseda, M., Beyna, M., Yokota, Y. & Iavarone, A. Nature 407, 592–598 (2000).

    Article  ADS  CAS  Google Scholar 

Download references

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Correspondence to Nick Dyson.

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Dyson, N. A twist in a mouse tale. Nature 421, 903–904 (2003). https://doi.org/10.1038/421903a

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