People with the genetic disease Peutz–Jeghers syndrome have many intestinal polyps — benign tissue outgrowths. These seldom become malignant, and the reason may lie in the properties of the affected gene.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Bardeesy, N. et al. Nature 419, 162–167 (2002).
Haggitt, R. C. & Reid, B. J. Am. J. Surg. Pathol. 10, 871–887 (1986).
Kinzler, K. W. & Vogelstein, B. Science 280, 1036–1037 (1998).
Wang, Z. J. et al. J. Pathol. 188, 613–617 (1999).
Ylikorkala, A. et al. Science 293, 1323–1326 (2001).
Miyoshi, H. et al. Cancer Res. 62, 2261–2266 (2002).
Jishage, K. et al. Proc. Natl Acad. Sci. USA 99, 8903–8908 (2002).
Sherr, C. J. Nature Rev. Mol. Cell Biol. 2, 731–737 (2001).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
van der Weyden, L., Jonkers, J. & Bradley, A. Stuck at first base. Nature 419, 127–128 (2002). https://doi.org/10.1038/419127a
Issue Date:
DOI: https://doi.org/10.1038/419127a