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Rabbits as models for impotence research

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References

  1. Thielen P, Renders M. . Influence de la stimulation des nerfs sensoriel de la region sacree sur la longueur du penis chez le lapin. Archives Internationales de Physiologie et de Biochemie 1967 75, 859–861

    Article  CAS  Google Scholar 

  2. Lin YM, Lin JS. . The rabbit as an intracavernous injection model. Urol Res 1996 24, 27–32.

    Article  CAS  Google Scholar 

  3. Sjöstrand NO, Klinge EK. . Principal mechanisms controlling penile retraction and protrusion in rabbit. Acta Physiol Scand 1979 106, 199–214.

    Article  Google Scholar 

  4. Anderson K-E, Wagner G. . Physiology of penile erection. Physiol Rev 1995 75, 191–236.

    Article  Google Scholar 

  5. Taub HC, Lerner SE, Melman A, Christ GJ. . Relationship between contraction and relaxation in human and rabbit corpus cavernosum. Urology 1993 42, 698–704.

    Article  CAS  Google Scholar 

  6. Azadzoi KM, Saenz de Tejada I, Goldstein I, Krane RJ. . Characterization of rabbit corpus cavernosum in vitro. Surgical Forum 1988 39, 660–661 Abstract published in the Proceedings of the 44th Annual Sessions of the Forum on Fundamental Surgical Problems—Clinical Congress, 23–28, October 1988, Chicago, Illinois.

    Google Scholar 

  7. Bush PA, Buga AWJ, Rajfer J, Ignarro LJ. . Nitric oxide is a potent relaxant of corpus cavernosum. J Urology 1992 147, 1660–1655.

    Article  Google Scholar 

  8. Azadoi KM, Goldstein I. . Erectile dysfunction due to atherosclerotic vascular disease: the development of an animal model. Urology 1992 147, 1675–1681.

    Article  Google Scholar 

  9. Azadoi KM et al. Relative roles of cyclooxygenase and nitric oxide synthase pathways in ischemia-induced increased contraction of cavernosal smooth muscle. Urology 1999 161, 1324–1328.

    Article  Google Scholar 

  10. Sullivan ME et al. Alterations in Endothelin B receptor sites in cavernosal tissue of diabetic rabbits: Potential relevance to the pathogenesis of erectile dysfunction. Urology 1997 158, 1966–1972.

    Article  CAS  Google Scholar 

  11. Sullivan M et al. Differential alterations of prostacyclin, cyclic AMP and cyclic GMP formation in the corpus cavernosum of the diabetic rabbit. Br Urol 1998 82, 578–584.

    Article  CAS  Google Scholar 

  12. Haas CA, Seftel AD. . Erectile dysfunction in aging: Upregulation of endothelial nitric oxide synthase. Urology 1998 51, 516–522.

    Article  CAS  Google Scholar 

  13. Azadoi KM et al. Relationship between cavernosal ischemia and corporal veno-occlusive dysfunction in an animal model. Urology 1997 157, 1011–1017.

    Article  Google Scholar 

  14. Stief CG et al.. The rabbit as model for neurourologic studies of the lower genitourinary tract. World J Urol 1990 8, 233–236.

    Article  Google Scholar 

  15. Naganuma H, Egashira T, Fujii J. . Neuroleptics induce penile erection in the rabbit. Clin Exper Pharmacol Physiol 1993 20, 177–183.

    Article  CAS  Google Scholar 

  16. Bischoff E et al.. Vardenafil a potent and selective inhibitor of phosphodiesterase type 5 increases cGMP in rabbit corpus cavernosum. Int J Impot Res 2000 12(suppl), S65.

    Google Scholar 

  17. Bischoff E et al.. The oral efficacy of vardenafil hydrochloride in inducing penile erections in a conscious rabbit model. J Urol 2001 165, 1316–1318.

    Article  CAS  Google Scholar 

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Bischoff, E. Rabbits as models for impotence research. Int J Impot Res 13, 146–148 (2001). https://doi.org/10.1038/sj.ijir.3900681

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