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Sharing gene expression data: an array of options

Nature Reviews Neuroscience volume 2, pages 435–438 (2001)Cite this article

Abstract

Sharing of microarray data has many advantages for the scientific and biomedical community, and should be advocated by neuroscience journals. The goals of sharing are manifold, and include improving analysis and confidence in results, and facilitating global comparisons between experiments, while at the same time, not penalizing those who share. The sharing of microarray data poses unique challenges relative to more generic data such as DNA sequences. These challenges are surmountable, and various sharing formats are possible. Centralized non-commercial databases are being developed to facilitate this process.

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Figure 1: Experimental stages in a typical cDNA microarray experiment.

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Acknowledgements

I am grateful to my colleagues Chiara Sabatti and Harley Kornblum, and to members of the Geschwind Laboratory, especially Joseph Dougherty, for their comments on the manuscript and helpful discussions. I thank Bonita Porch for her editorial assistance.

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Authors and Affiliations

  1. the Department of Neurology, University of California, Los Angeles, School of Medicine, 710 Westwood Plaza, Los Angeles, 90095-1769, California, USA

    Daniel H. Geschwind

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  1. Daniel H. Geschwind
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FURTHER INFORMATION

Autism Genetic Resource Exchange

Minimal Information About a Microarray Experiment

Microarray Gene Expression Database Group

Gene Expression Omnibus

ArrayExpress

GeneX

Y. Kagami

Draft recommendations of the MGED

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Geschwind, D. Sharing gene expression data: an array of options. Nat Rev Neurosci 2, 435–438 (2001). https://doi.org/10.1038/35077576

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