There are 'roadblocks' at several points in the signalling pathways that control programmed cell death. When the cell needs to die, these roadblocks must be removed, and a vertebrate protein that removes one such block has now been identified.
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De Laurenzi, V., Melino, G. The little devil of death. Nature 406, 135–136 (2000). https://doi.org/10.1038/35018190
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DOI: https://doi.org/10.1038/35018190
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