Sequencing DNA is a labour intensive and expensive process. At an estimated cost of $3–5 (US) per base pair, it would require about $25 million (US) to complete the sequence of Escherichia coli1.
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Cathcart, R. Advances in automated DNA sequencing. Nature 347, 310 (1990). https://doi.org/10.1038/347310a0
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DOI: https://doi.org/10.1038/347310a0