Efforts to alter the mAb component of pharmaceuticals have focused on making them more human-lIke and smaller. Ultimately, the smallest molecular recognition unit derived from antibodies may be a single complementarity region.
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Rodwell, J. Engineering monoclonal antibodies. Nature 342, 99–100 (1989). https://doi.org/10.1038/342099a0
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DOI: https://doi.org/10.1038/342099a0
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