Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Product Review
  • Published:

Retro-secretion of recombinant proteins

Nature volume 340, pages 323–324 (1989)Cite this article

The retroviral Gag protein can be used to package recombinant proteins produced by mammalian cell cultures. Protein products can then be isolated easily from the recombinant virions.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Smith, R.E. Meth. Enzymol. 58, 393 (1979).

    Article  ADS  CAS  Google Scholar 

  2. Dickson, C., Eisenman, R., Fan, H., Hunter, E. & Teich, N. in RNA Tumor Viruses Vol. 1 (eds Weiss, R., Teich, N., Varmus, H. & Coffin, J.) 513–648 (Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, 1984).

    Google Scholar 

  3. Voynow, S.L. & Coffin, J.M. J. Virol 55, 79 (1985).

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Weldon, R.A., Erdie, C.R. & Wills, J.W. (in preparation).

  5. Adams, S.E., Dawson, K.M., Gull, K., Kingman, S.M. & Kingman, A.J. Nature 329, 68 (1987).

    Article  ADS  CAS  PubMed  Google Scholar 

  6. Weiss, R. in RNA Tumor Viruses Vol. 1 (eds Weiss, R., Teich, N., Varmus, H. & Coffin, J.) 209–260 (Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, 1984).

    Google Scholar 

  7. Vogt, V.M., Bruckenstein, D.A. & Bell, A.P. J. Virol. 44, 725 (1982).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Schultz, A.M., Henderson, L.E. & Oroszlan, S. Ann. Rev. Cell Biol. 4 611 (1988).

    Article  CAS  PubMed  Google Scholar 

  9. Towler, D.A., Gordon, J.I., Adams, S. P. & Glaser, L. Ann. Rev. Biochem. 57, 69 (1988).

    Article  CAS  PubMed  Google Scholar 

  10. Rein, A., McClure, M.R., Rice, N.R., Luftig, R.B. & Schultz, A.M. Proc. natn Acad. Sci. U.S.A. 83, 7246 (1986).

    Article  ADS  CAS  Google Scholar 

  11. Rhee, S.S. & Hunter, E. J. Virol. 61, 1045 (1987).

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Wills, J.W., Craven, R.C. & Achacoso, J.A. J. Virol. (in the press).

  13. Leis, J. et al. J. Virol. 62, 1808 (1988).

    CAS  PubMed  PubMed Central  Google Scholar 

  14. Skalka, A.M. Cell 56, 911 (1989).

    Article  CAS  PubMed  Google Scholar 

  15. Smith, M., Leung, D.W., Gillam, S. & Astell, C.R. Cell 16, 753 (1979).

    Article  CAS  PubMed  Google Scholar 

  16. Felsenstein, K.M. & Goff, S.P. J. Virol. 62, 2179 (1988).

    CAS  PubMed  PubMed Central  Google Scholar 

  17. Perez, L.G., Davis, G.L. & Hunter, E. J. Virol. 61, 2981 (1987).

    CAS  PubMed  PubMed Central  Google Scholar 

  18. Wilson, C., Reitz, M.S., Okayama, H. & Eiden, M.V. J. Virol. 63, 2374 (1989).

    CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Louisiana State University Medical Center–Shreveport, 1501 Kings Highway, P.O. Box 33932, Shreveport, Louisiana, 71130, USA

    J. W. Wills

Authors
  1. J. W. Wills
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wills, J. Retro-secretion of recombinant proteins. Nature 340, 323–324 (1989). https://doi.org/10.1038/340323a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/340323a0

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing