Abstract
The Tetrahymena ribozyme can splice together multiple oligonucleotides aligned on a template strand to yield a fully complementary product strand. This reaction demonstrates the feasibility of RNA-catalysed RNA replications.
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Doudna, J., Szostak, J. RNA-catalysed synthesis of complementary-strand RNA. Nature 339, 519–522 (1989). https://doi.org/10.1038/339519a0
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DOI: https://doi.org/10.1038/339519a0
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