Abstract
Three independent pseudoautosomal loci are linked to sex determination at frequencies which define a gradient of linkage. The segregation patterns of these loci indicate that X/Y recombination results from a single obligatory meiotic crossing-over in the pseudoautosomal region. Recombination in male germ cells in the terminal regions of the short arms of the X and Y chromosomes is 10-fold greater than between the same regions of the X chromosomes infernale germ cells.
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Rouyer, F., Simmler, MC., Johnsson, C. et al. A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes. Nature 319, 291–295 (1986). https://doi.org/10.1038/319291a0
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DOI: https://doi.org/10.1038/319291a0
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