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Expression of two proteins from overlapping and oppositely oriented genes on transposable DNA insertion element IS5

Abstract

IS5, the 1,195 base pair transposable DNA element of Escherichia coli, contains two genes. One gene, which encodes a protein with an apparent molecular weight of 12,300, is, together with its promoter, completely contained within a larger gene which encodes a protein of molecular weight 37,000. The two genes are transcribed in opposite directions.

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Rak, B., Lusky, M. & Hable, M. Expression of two proteins from overlapping and oppositely oriented genes on transposable DNA insertion element IS5. Nature 297, 124–128 (1982). https://doi.org/10.1038/297124a0

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