Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

A new protein that gels F actin in the cell cortex of Dictyostelium discoideum

Abstract

It is thought that the dense actin filament networks found in the cortex of many cell types1–4 might account for the gelled consistency of the cortex5 and the exclusion of other organelles from this region of the cytoplasm6–8. We now demonstrate that a new actin-binding protein from Dictyostelium that gels actin in vitro is concentrated in the cell cortex, suggesting that this protein, in association with actin, accounts for the gel-like properties of this region of the cell.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Mooseker, M. & Tilney, L. J. Cell Biol. 67, 725–743 (1975).

    Article  CAS  Google Scholar 

  2. Goldman, A., Yerna, M. & Schloss, J. J. supramolec. Struct. 5, 155–183 (1976).

    Article  CAS  Google Scholar 

  3. Begg, D., Roderwald, R. & Rebhun, L. J. Cell Biol. 79, 846–852 (1978).

    Article  CAS  Google Scholar 

  4. Condeelis, J. & Wolosewick, J. Proc. 38th Meet. Electron Miscrosc. Soc. Am. 420–423 (1980).

  5. Taylor, D. & Condeelis, J. Int. Rev. Cytol. 56, 57–143 (1979).

    Article  CAS  Google Scholar 

  6. Condeelis, J. Int. Cell Biol. (ed. Schweiger, H.) 306–320 (Springer, Berlin, (1980/81).

  7. Wolosewick, J. & Porter, K. J. Cell Biol. 82, 114–139 (1979).

    Article  CAS  Google Scholar 

  8. Woloswick, J. & Condeelis, J. Cell (in the press).

  9. Condeelis, J. Neurosci. Res. Prog. Bull. 19, 83–99 (1981).

    CAS  Google Scholar 

  10. Condeelis, J. & Geosits, S. J. biol Chem. (in the press).

  11. Fujiwara, K. & Pollard, T. J. Cell Biol. 71, 848–875 (1976).

    Article  CAS  Google Scholar 

  12. Stendahl, O., Hartwig, J., Brotschi, E. & Stossel, T. J. Cell Biol. 84, 215–224 (1980).

    Article  CAS  Google Scholar 

  13. Heggeness, M., Wang, K. & Singer, S. J. Proc. natn. Acad. Sci. U.S.A. 74, 3883–3887 (1977).

    Article  ADS  CAS  Google Scholar 

  14. Eckert, B. & Lazarides, E. J. Cell Biol. 77, 714–721 (1978).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Coudeelis, J., Salisbury, J. & Fujiwara, K. A new protein that gels F actin in the cell cortex of Dictyostelium discoideum. Nature 292, 161–162 (1981). https://doi.org/10.1038/292161a0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/292161a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing