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A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virus

Nature volume 292, pages 31–35 (1981)Cite this article

Abstract

The human genome contains a single and constant locus (c-sis) related to the transforming gene (v-sis) of simian sarcoma virus. The isolation of a recombinant phage containing the entire human c-sis gene has allowed the study of its genomic organization: c-sis extends over a region of ∼12 kilobases (kb) which includes 1.2 kb of v-sis-related sequences interrupted by four intervening sequences.

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Authors and Affiliations

  1. Laboratory of Tumor Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205, USA

    Riccardo Dalla Favera, Edward P. Gelmann, Robert C. Gallo & Flossie Wong-Staal

Authors
  1. Riccardo Dalla Favera
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  2. Edward P. Gelmann
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  3. Robert C. Gallo
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  4. Flossie Wong-Staal
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Favera, R., Gelmann, E., Gallo, R. et al. A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virus. Nature 292, 31–35 (1981). https://doi.org/10.1038/292031a0

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