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A model from electron microscopy for the molecular structure of fibrinogen and fibrin

Abstract

The overall architecture of the fibrinogen molecule and aspects of its packing to form fibrin have been derived from a study of electron microscope images of ordered arrays. The molecule, of length 450 Å, is seen in more detail than the Hall–Slayter model and is made up of seven globular domains connected by rod-like segments.

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Weisel, J., Phillips, G. & Cohen, C. A model from electron microscopy for the molecular structure of fibrinogen and fibrin. Nature 289, 263–267 (1981). https://doi.org/10.1038/289263a0

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