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Invertible DNA determines host specificity of bacteriophage Mu

Abstract

The function of the invertible G region of bacteriophage Mu is apparently to confer different host specificities on Mu. Two products of genes S and U, situated in the G region are not needed for the infectivity of Mu G(−) particles. In the Mu G(−) phage the S gene product and the 21-K polypeptide, presumably the product of gene U, are missing. Instead, two other polypeptides with different molecular weights are observed.

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van de Putte, P., Cramer, S. & Giphart-Gassler, M. Invertible DNA determines host specificity of bacteriophage Mu. Nature 286, 218–222 (1980). https://doi.org/10.1038/286218a0

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