Abstract
Two protein factors which bind to, and induce gelation of, actin filaments were purified from Ehrlich tumour cells. Filamin induced Ca2+-insensitive gelation, whereas a new protein factor (‘actinogelin’) was found to induce Ca2+-sensitive gelation.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Pollard, T. D. J. Cell Biol. 68, 579–601 (1976).
Maruta, H. & Korn, E. D. J. biol. Chem 252, 399–402 (1977).
Condeelis, J. S. & Taylor, D. L. J. Cell Biol. 74, 901–927 (1977).
Stossel, T. P. & Hartwig, J. A. J. Cell Biol. 68, 602–619 (1976).
Weihing, R. R. J. Cell Biol. 71, 303–307 (1976).
Mirura, N. & Asano, A. Nature 272, 273–276 (1978).
Kane, R. E. J. Cell Biol. 71, 704–714 (1976).
Taylor, D. L. Expl Cell Res. 105, 413–426 (1977).
Nacchache, P. H., Volpi, M., Showell, H. J., Becker, E. L. & Sha'afi, R. I. Science 203, 461–463 (1979).
Theoharides, T. C. & Douglas, W.W. Science 201, 1143–1145 (1978).
Rahamimoff, R., Meiri, H., Erulkar, S. D. & Barenholz, Y. Proc. natn. Acad. Sci. U.S.A. 75, 5214–5216 (1978).
Fulton, B. P. & Whitlingham, D. G. Nature 273, 149–151 (1978).
Clark, T. G. & Merrian, R. W. J. Cell Biol. 77, 427–438 (1978).
Okada, Y. & Murayama, F. Expl Cell Res. 44, 527–551 (1966).
Ohki, K., Asano, A. & Okada, Y. Biochim. biophys. Acta 507, 507–516 (1978).
Volsky, D. J. & Loyter, A. J. Cell Biol. 78, 465–479 (1978).
Blow, A. M. J. et al. FEBS Lett. 94, 305–310 (1978).
Shainberg, A., Yagil, G. & Yafe, D. Devl Biol. 25, 1–29 (1971).
Shizuta, Y. et al. J. biol. Chem. 251, 6562–6567 (1976).
Wang, K. Biochemistry 16, 1857–1865 (1977).
Brotschi, E., Hartwig, J. H. & Stossel, T. P. J. biol. Chem. 253, 8988–8993 (1978).
Bryan, J. & Kane, R. E. J. molec. Biol. 125, 207–224 (1978).
Yin, H. L. & Stossel, T. P. J. Cell Biol. 79, 271a (1978).
Virgin, H. W., Hellewell, S. B. & Taylor, D. L. J. Cell Biol. 79, 265a (1978).
Weihing, R. R. J. Cell Biol. 75, 95–103 (1977).
Boxer, L. A. & Stossel, T. P. J. clin. Invest. 57, 964–976 (1976).
Davies, P. J. A. et al. J. biol. Chem. 253, 4036–4042 (1978).
Kakiuchi, S., Yamazaki, R., Teshima, Y., Uenishi, K. & Miyamoto, E. Proc. natn. Acad. Sci. U.S.A. 70, 3526–3530 (1973).
Lin, Y. M., Lin, Y. P. & Cheung, W. Y. J. biol. Chem. 249, 4943–4954 (1974).
Mikawa, T., Nonomura, Y., Hirata, M., Ebashi, S. & Kakiuchi, S. J. Biochem. (Tokyo) 84, 1633–1636 (1978).
Davies, P., Bechtel, P. & Pastan, I. FEBS Lett. 77, 228–232 (1977).
Moore, P. B. & Carraway, K. L. Biochem. biophys. Res. Commun. 80, 560–567 (1978).
Lazarides, E. J. Cell Biol. 68, 202–209 (1976).
Maruyama, K. & Ebashi, S. J. Biochem. (Tokyo) 58, 13–19 (1965).
Briskey, E. J., Seraydarian, K. & Mommerts, W. F. H. M. Biochim. biophys. Acta 133, 424–434 (1967).
Ishiwata, S. Biochim. biophys. Acta 303, 77–89 (1973).
Ishiwata, S. Biochim. biophys. Acta 534, 350–357 (1978).
Spudich, J. A., Mockrin, S. C., Brown, S. S., Rubenstein, P. A. & Levinson, W. in Cell Shape and Surface Architecture (eds Revel, J. P., Henning, U. & Fox, C. F.) 545–558 (Liss, New York, 1977).
Griffith, L. M. & Pollard, T. D. J. Cell Biol. 78, 958–965 (1978).
Schook, W., Puszikin, S., Bloom, W., Ores, C. & Kochwa, S. Proc. natn. Acad. Sci. U.S.A. 76, 116–120 (1979).
Korn, E. D. Proc. natn. Acad. Sci. U.S.A. 75, 588–599 (1978).
Lowry, O. H., Rosebrough, N. J., Farr, A. L. & Randall, R. J. J. biol. Chem. 193, 265–275 (1951).
Ogawa, Y. J. Biochem. (Tokyo) 64, 255–257 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Mimura, N., Asano, A. Ca2+-sensitive gelation of actin filaments by a new protein factor. Nature 282, 44–48 (1979). https://doi.org/10.1038/282044a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/282044a0
This article is cited by
-
A novel protein accumulated during maturation of the pods of the plantImpatiens balsamina
Molecular and Cellular Biochemistry (1994)
-
In vitro effects of PAF on venous endothelial cell actin disposition
Agents and Actions (1992)
-
Diffusion of ions and indicator dyes in neural cytoplasm
Cellular and Molecular Neurobiology (1984)
-
Chromaffin granule membrane–F-actin interactions are calcium sensitive
Nature (1982)
-
Actin-binding proteins—regulators of cell architecture and motility
Nature (1982)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.