Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Neuronal localisation of immunoreactive enkephalin and β-endorphin in the earthworm

Abstract

SINCE the report by Simantov et al.1 invertebrates have been thought to lack endogenous opiates and opiate receptors. As we have previously observed peptidergic neurones containing immunoreactive pancreatic polypeptide or vasoactive intestinal peptide in the earthworm2, we decided to search for, and report here our finding of, nerves storing immunoreactive enkephalin or β-endorphin in this species.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Simantov, R., Goodman, R., Aposhiau, D. & Snyder, S. H. Brain Res. 111, 204–211 (1976).

    Article  CAS  Google Scholar 

  2. Sundler, F., Håkanson, R., Alumets, J. & Walles, B. Brain Res. Bull. 2, 61–65 (1977).

    Article  CAS  Google Scholar 

  3. Coons, A. H., Leduc, E. H. & Connolly, J. M. J. exp. Med. 102, 49–60 (1955).

    Article  CAS  Google Scholar 

  4. Sternberger, L. A. Immunocytochemistry (Prentice-Hall, New Jersey, 1974).

    Google Scholar 

  5. Miller, R. J., Chang, K.-J., Cooper, B. & Cuatrecasas, P. J. biol. Chem. 253, 531–538 (1978).

    CAS  Google Scholar 

  6. Alumets, J., Håkanson, R., Sundler, F. & Chang, K.-J. Histochemistry 56, 187–196 (1978).

    Article  CAS  Google Scholar 

  7. Rémy, C. & Dubois, M. P. Experientia 35, 137–138 (1978).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

ALUMETS, J., HÅKANSON, R., SUNDLER, F. et al. Neuronal localisation of immunoreactive enkephalin and β-endorphin in the earthworm. Nature 279, 805–806 (1979). https://doi.org/10.1038/279805a0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/279805a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing