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Gene fusion during the evolution of the tryptophan operon in Enterobacteriaceae

Abstract

THE genes of tryptophan biosynthesis are organised differently in various species of microorganisms1. In several organisms it seems that gene fusions have joined functionally distinct polypeptide chains into single bifunctional proteins. Here we present our analysis of one example of a possible gene fusion and an attempt to deduce the sequence of events responsible.

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MIOZZARI, G., YANOFSKY, C. Gene fusion during the evolution of the tryptophan operon in Enterobacteriaceae. Nature 277, 486–489 (1979). https://doi.org/10.1038/277486a0

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