Abstract
THE taxonomic group of papova viruses comprises a number of small icosahedral virus species, all isolated from mammals. The members of this group, such as papilloma, polyoma and the so-called vacuolating Simian virus 40 (SV40) contain double-stranded circular closed DNA. All are oncogenic, capable of transforming cells in vitro. Some viruses of this group which are called BK1 and JC2 have been isolated from human patients—BK-virus is apparently widespread, as more than 80% of the human population harbour antibodies against this virus3. We describe here a new member of the papova virus group, designated HD-virus, which we have isolated in our laboratory from primate cells (VERO-cells—a permanent line derived from Cercopithecus aethiops monkey kidney cells4—which have been routinely passaged for several years in our laboratory). HD-virus is capable of rapidly transforming cells in vitro.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Gardner, S. D., Field, A. M., Coleman, D. V. & Hulme, B. Lancet i, 1253 (1971).
Padgett P. L., Walter, D. L., Zu Rhein, G. M., Eckroade, R. J., & Dessel, B. H. Lancet i, 1257 (1971).
Gardner, S. D., Br. med. J. 1, 77 (1973).
Yasumura, T. & Kawakita, Y. Nippon Rinsho 21, 1201 (1963).
Radloff, R., Bauer, W. & Vinograd, J., Proc. natn. Acad. Sci. U.S.A. 57, 1514 (1967).
Waldeck, W., Chowdhury, K., Gruss, P. & Sauer, G., Biochim. biophys. Acta 425, 157 (1976).
Kuhn, C., Waldeck, W. & Sauer, G., Z. Krebsforsch. 83, 65 (1975).
Khoury, G., Howley, P. M., Baron, G. & Mullerkey, M. F., Proc. natn. Acad. Sci. U.S.A. 72, 2563 (1975).
Osborn, J. E., Robertson, S. M., Padgett, B. L., Walter, D. L. & Weisblum, B., J. Virol. 19, 675 (1976).
Ferguson, J. & Davis, R. W. J. molec. Biol. 94, 496 (1976).
Macpherson, I. & Montagnier, L. Virology 23, 291 (1964).
Clarke, G. D., Stoker, M. G. P., Ludlow, A. & Thornton, M. Nature 227, 798 (1970).
Dulbecco, R. Nature 227, 802 (1970).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WALDECK, W., SAUER, G. New oncogenic papova virus from primate cells. Nature 269, 171–173 (1977). https://doi.org/10.1038/269171a0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/269171a0
This article is cited by
-
Human exposure to bovine polyomavirus: A zoonosis?
Archives of Virology (1986)
-
Characterisation of a Polyomavirus in two foetal rhesus monkey kidney cell lines used for the growth of hepatitis A virus
Archives of Virology (1984)
-
Evidence for a bovine origin of the polyomaviurs detected in foetal rhesus monkey kidney cells, FRhK-4 and -6
Archives of Virology (1983)
-
Papovavirus-related RNA sequences in human neurogenic tumours
Acta Neuropathologica (1982)
-
Lymphotropic papovaviruses isolated from African green monkey and human cells
Medical Microbiology and Immunology (1979)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
