Abstract
WE describe here the development of a new analytical configuration, called a microbe thermistor, in which immobilised microorganisms are placed in proximity to a thermistor which measures the metabolic heat evolved by them. Many metabolites can thus be analysed, as we show here by the determination of both single components such as glucose and fructose and of more complex mixtures such as casein. This is in contrast to other analytical applications of immobilised enzymes, for example enzyme electrodes1–3 and enzyme thermistors4–6, which can normally allow analysis of only one compound at a time.
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MATTIASSON, B., LARSSON, PO. & MOSBACH, K. The microbe thermistor. Nature 268, 519–520 (1977). https://doi.org/10.1038/268519a0
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DOI: https://doi.org/10.1038/268519a0
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