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Proviral sequences of baboon endogenous type C RNA virus in DNA of human leukaemic tissues

Nature volume 262, pages 190–195 (1976)Cite this article

Abstract

Hybridisation of RNA from a baboon endogenous type C RNA virus to DNA from tissues of leukaemic patients indicates that a virus of this type is horizontally transmitted among humans. DNA from several patients with leukaemia hybridised 70% of the hybridisable RNA from baboon endogenous type C RNA virus (BaEV) and yielded hybrids of high tm, whereas DNA from normal human tissues hybridised only 23% of the BaEV RNA, and the tm of these hybrids was lower.

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References

  1. Sarngadharan, M. G., Sarin, P. S., Reitz, M. S., and Gallo, R. C., Nature new Biol., 244, 206 (1973).

    Google Scholar 

  2. Todaro, G. J., and Gallo, R. C., Nature new Biol., 244, 206 (1973).

    Article  CAS  Google Scholar 

  3. Gallagher, R. E., Todaro, G. J., Smith, R. G., Livingston, D. M., and Gallo, R. C., Proc. natn. Acad. Sci. U.S.A., 71, 1209 (1974).

    Article  Google Scholar 

  4. Gallo, R. C., et al., Cold Spring Harb. Symp. quant. Biol., 39, 933 (1974).

    Article  Google Scholar 

  5. Gillespie, D. H., Saxinger, W. C., and Gallo, R. C., Prog. Nucl. Acid. Res. molec. Biol., 15, 1 (1975).

    Article  CAS  Google Scholar 

  6. Gallo, R. C., Saxinger, W. C., Miller, N. R., and Gillespie, D. H., Proc. natn. Acad. Sci. U.S.A., 70, 3219 (1973).

    Article  CAS  Google Scholar 

  7. Miller, N., et al., Proc. natn. Acad. Sci. U.S.A., 71, 3177 (1974).

    Article  CAS  Google Scholar 

  8. Baxt, W., Hehlman, R., and Spiegelman, S., Nature new Biol., 240, 72 (1972).

    Article  CAS  Google Scholar 

  9. Kufe, D., Hehlman, R., and Spiegelman, S., Science, 175, 182 (1972).

    Article  CAS  Google Scholar 

  10. Baxt, W., and Spiegelman, S., Proc. natn. Acad. Sci. U.S.A., 69, 3737 (1972).

    Article  CAS  Google Scholar 

  11. Baxt, W., Yates, J. W., Wallace, H. J., Holland, J. F., and Spiegelman, S., Proc. natn. Acad. Sci. U.S.A., 70, 2629 (1973).

    Article  CAS  Google Scholar 

  12. Kotler, M., Weinberg, E., Haspel, O., Olshevsky, U., and Becker, Y., Nature new Biol., 244, 197 (1973).

    Article  CAS  Google Scholar 

  13. Mak, T. W., Kurtz, S., Manaster, J., and Housman, D., Proc. natn. Acad. Sci. U.S.A., 72, 623 (1975).

    Article  CAS  Google Scholar 

  14. Gallagher, R. E., and Gallo, R. C., Science, 197, 350 (1974).

    Google Scholar 

  15. Teich, N. M., et al., Nature, 256, 551 (1975).

    Article  CAS  Google Scholar 

  16. Gallagher, R. E., Salahuddin, S. Z., Hall, W. T., McCredie, K. B., and Gallo, R. C., Proc. natn. Acad. Sci. U.S.A., 72, 4137 (1975).

    Article  CAS  Google Scholar 

  17. Panem, S., Prochownik, E. V., Reale, F. R., and Kirsten, W. H., Science, 189, 297 (1975).

    Article  CAS  Google Scholar 

  18. Nooter, K., Aarssen, A. M., Bentvelzen, P., and d'Groot, F. G., Nature, 256, 595 (1975).

    Article  CAS  Google Scholar 

  19. Gabelman, N., Waxman, S., Smith, W., and Douglas, S. D., Int. J. Cancer, 16, 355 (1975).

    Article  CAS  Google Scholar 

  20. Temin, H., Natn. Cancer Inst. Monogr., 17, 557 (1964).

    Google Scholar 

  21. Todaro, G. J., Sherr, C. J., Benveniste, R. E., and Lieber, M. M., Cell, 2, 55 (1974).

    Article  CAS  Google Scholar 

  22. Benveniste, R. E., Lieber, M. M., Livingston, D. M., Sherr, C. J., and Todaro, G. J., Nature, 248, 17 (1974).

    Article  CAS  Google Scholar 

  23. Benveniste, R. E., Sherr, C. J., Lieber, M. M., Callahan, R., and Todaro, G. J., in Fundamental Aspects of Neoplasm (edit. by Gottleib, A.), 29 (Springer, New York, 1975).

    Book  Google Scholar 

  24. Benveniste, R. E., and Todaro, G. J., Nature, 252, 170 (1974).

    Article  CAS  Google Scholar 

  25. Reitz, M. S., et al., Proc. natn. Acad. Sci. U.S.A., 73, 2113 (1976).

    Article  CAS  Google Scholar 

  26. Rice, N., in Evolution or Genetic Systems (edit. by H. H. Smith), 44 (Gordon and Breach, New York, 1972).

    Google Scholar 

  27. Wong-Staal, F., Gallo, R. C., and Gillespie, D., Nature, 256, 670 (1975).

    Article  CAS  Google Scholar 

  28. Sherr, C. J., and Todaro, G. J., Proc. natn. Acad. Sci. U.S.A., 71, 4703 (1974).

    Article  CAS  Google Scholar 

  29. Sherr, C. J., and Todaro, G. J., Science. 197, 855 (1975).

    Article  Google Scholar 

  30. Strand, M., and August, J. T., J. Virol., 14, 1584 (1974).

    CAS  PubMed  PubMed Central  Google Scholar 

  31. Baxt, W., Proc. natn. Acad. Sci. U.S.A., 71, 2835 (1974).

    Article  Google Scholar 

  32. Larson, C. J., et al., Proc. natn. Acad. Sci. U.S.A., 72, 4900 (1975).

    Article  Google Scholar 

  33. Prochownik, E. V., and Kirsten, W. H., Nature, 260, 64 (1976).

    Article  CAS  Google Scholar 

  34. Aoki, T., Walling, M. J., Bushar, G. S., Liu, M., and Hsu, K. C., Proc. natn. Acad. Sci. U.S.A. (in the press).

  35. Metzgar, R. S., Mohanakumar, T., and Bolognesi, D. P., J. exp. Med., 143, 47–63 (1976).

    Article  CAS  Google Scholar 

  36. Gillespie, D., and Gallo, R. C., VII Int. Symp. Comparative Research on Leukemia and Related Diseases (S. Karger, New York, in the press).

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Authors and Affiliations

  1. Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014

    Flossie Wong-Staal, David Gillespie & Robert C. Gallo

Authors
  1. Flossie Wong-Staal
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  2. David Gillespie
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  3. Robert C. Gallo
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Wong-Staal, F., Gillespie, D. & Gallo, R. Proviral sequences of baboon endogenous type C RNA virus in DNA of human leukaemic tissues. Nature 262, 190–195 (1976). https://doi.org/10.1038/262190a0

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