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4S oop RNA is a leader sequence for the immunity-establishment transcription in coliphage λ

Nature volume 262, pages 112–116 (1976)Cite this article

Abstract

oop RNA, which is initiated at the po promoter and is 81 nucleotides long, can function as a leader sequence for the λ immunity establishment transcription, previously believed to originate at a special promoter pre located in the y region. Thus, oop RNA seems to have a dual role, either favouring the lytic cycle as a primer for the initiation of λ DNA replication, or leading to the establishment of lysogeny when elongated into the imm transcript, which directs synthesis of the repressor.

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Authors and Affiliations

  1. McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, Wisconsin, 53706

    A. Honigman, S.-L. Hu, R. Chase & W. Szybalski

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  1. A. Honigman
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  2. S.-L. Hu
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  3. R. Chase
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  4. W. Szybalski
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Honigman, A., Hu, SL., Chase, R. et al. 4S oop RNA is a leader sequence for the immunity-establishment transcription in coliphage λ. Nature 262, 112–116 (1976). https://doi.org/10.1038/262112a0

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