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Changes in histone f2a2 associated with proliferation of Friend leukaemic cells

Abstract

HISTONE–HISTONE interactions with DNA form the basic structural unit of chromatin1–3, and quantitative changes in the cellular histones correlate with alterations in chromatin structure4,5. More subtle changes in chromatin structure follow chemical modification of the histones. These changes may enable genes to assume proper configuration for specific regulation by the non-histone proteins.

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BLANKSTEIN, L., LEVY, S. Changes in histone f2a2 associated with proliferation of Friend leukaemic cells. Nature 260, 638–640 (1976). https://doi.org/10.1038/260638a0

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