Abstract
HISTONE–HISTONE interactions with DNA form the basic structural unit of chromatin1–3, and quantitative changes in the cellular histones correlate with alterations in chromatin structure4,5. More subtle changes in chromatin structure follow chemical modification of the histones. These changes may enable genes to assume proper configuration for specific regulation by the non-histone proteins.
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References
Kornberg, R. D., and Thomas, J. D., Science, 184, 865–871 (1974).
Olins, A., and Olins, D., Science, 183, 330–332 (1974).
Baldwin, J. P., Boseley, P. G., Bradbury, E. M., and Ibel, K., Nature, 253, 245–249 (1975).
Bloch, D. P., Genetics, 61, 93–110 (1969).
Allfrey, V. G., Histones and Nucleohistones (edit. by Phillips, D. M. P.), 241–294 (Plenum, London and New York, 1971).
Ostertag, W., Melderis, H., Steinheider, G., Kluge, N., and Dube, S., Nature new Biol., 239, 231 (1972).
Ross, J., Ikawa, Y., and Leder, P., Proc. natn. Acad. Sci., U.S.A., 69, 3620 (1972).
Friend, C., Scher, W., Holland, J. G., and Sato, T., Proc. natn. Acad. Sci., U.S.A., 68, 378 (1971).
Reem, G. H., and Friend, C., Proc. natn. Acad. Sci., U.S.A., 72, 1630 (1975).
Sato, T., Friend, C., and DeHarven, E., Cancer Res., 31, 1402 (1971).
Levy, J., Terada, M., Rifkind, R., and Marks, P., Proc. natn. Acad. Sci. U.S.A., 72, 28 (1975).
Tanaka, M., Proc. natn. Acad. Sci. U.S.A., 72, 1003 (1975).
Nakanishi, S., Adhya, S., Gottesman, M., and Pastan, L., Cell, 3, 39 (1974).
Lapeyre, J. N., and Bekhor, I. J., J. molec. Biol., 89, 137 (1974).
Panyim, S., and Chalkley, R., Archs Biochem. Biophys., 130, 337 (1969).
Zweidler, A., and Cohen, L., Fedn Proc., 31, 926 (1972).
Alfageme, C. R., Zweidler, A., Mahowald, A., and Cohen, L., J. biol. Chem., 249, 3729 (1974).
Cohen, L., Newrock, K. M., and Zweidler, A., J. Cell Biol., 67, 75a (1975).
Haussler, M. R., Thomson, W. W., and Norman, A. W., Expl Cell Res., 58, 234 (1969).
Wright, E. B., and Olins, D. E., Biochem. biophys. Res. Commun., 63, 642 (1975).
McClintock, P. R., and Papaconstantinou, J., Proc. natn. Acad. Sci. U.S.A., 71, 4551 (1974).
Johns, E. W., Biochem. J., 92, 55 (1964).
Stollar, D. B., and Ward, M., J. biol. Chem., 245, 1261 (1970).
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BLANKSTEIN, L., LEVY, S. Changes in histone f2a2 associated with proliferation of Friend leukaemic cells. Nature 260, 638–640 (1976). https://doi.org/10.1038/260638a0
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DOI: https://doi.org/10.1038/260638a0
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