Abstract
Electron microscopic examination of a composite R plasmid made up of an RTF component and an r-determinants component shows that replication may originate from either the RTF origin or the r-determinants origin of replication.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Clowes, R., Bact. Rev., 36, 361–405 (1972).
Davies, J. E., and Rownd, R., Science, 716, 758–768 (1972).
Helinski, D. R., A. Rev. Microbiol., 27, 437–470 (1973).
Cohen, S. N., and Miller, C. A., J. molec. Biol., 50, 671–687 (1970).
Rownd, R., and Mickel, S., Nature new Biol., 234, 40–43 (1971).
Rownd, R., Kasamatsu, H., and Mickel, S., Ann. N.Y. Acad. Sci., 182, 188–206 (1971).
Rownd, R., Perlman, D., Hashimoto, H., Mickel, S., Appelbaum, E., and Taylor, D., in Cellular modification and genetic transformation by exogenous nucleic acids. Proc. sixth Miles Int. Symp. molec. Biol. (edit. by Beers, R. F., Jr, and Tilghman, R. C.), 115–128 (The Johns Hopkins University Press, Baltimore, 1973).
Nisioka, T., Mitani, M., and Clowes, R., J. Bact., 103, 166–177 (1970).
Perlman, D., and Rownd, R., J. Bact., 123, 1013–1034 (1975).
Rownd, R., Perlman, D., and Goto, N., in Microbiology-1974 (edit. by Schlesinger, D.), 76–94 (American Society for Microbiology, Washington, DC 1975).
Perlman, D., and Rownd, R., Molec. gen. Genet., 138, 281–291 (1975).
Perlman, D., Twose, T., Holland, M., and Rownd, R., J. Bact., 123, 1035–1042 (1975).
Masters, M., and Broda, P., Nature new Biol., 232, 137–140 (1971).
Bird, R. E., Lauarn, J., Martuscelli, J., and Caro, L., J. molec. Biol., 70, 549–566 (1972).
Morris, C., Hashimoto, H., Mickel, S., and Rownd, R., J. Bact., 118, 855–866 (1974).
Schnös, M., and Inman, R., J. molec. Biol., 51, 61–73 (1970).
Tomizawa, J., Sakakibara, Y., and Kakefuda, T., Proc. natn. Acad. Sci. U.S.A., 71, 2260–2264 (1974).
Inselburg, J., Proc. natn. Acad. Sci. U.S.A., 71, 2256–2259 (1974).
Lovett, M. A., Katz, L., and Helinski, D. R., Nature, 251, 337–340 (1974).
Newlon, C. S., Petes, T. D., Hereford, L. M., and Fangman, W. L., Nature new Biol., 247, 32–35 (1974).
Huberman, J. A., and Riggs, D. A., J. molec. Biol., 32, 327–341 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Perlman, D., Rownd, R. Two origins of replication in composite R plasmid DNA. Nature 259, 281–284 (1976). https://doi.org/10.1038/259281a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/259281a0
This article is cited by
-
Evidence for two distinct origins of replication in the large endogenous plasmid of Anacystis nidulans R2
Molecular and General Genetics MGG (1985)
-
DNA fusion product of phage P2 with plasmid pBR322: A new phasmid
Molecular and General Genetics MGG (1983)
-
Multiply branched replicative intermediates in E. coli and bacteriophage λ
Molecular and General Genetics MGG (1981)
-
Plasmid replication functions
Molecular and General Genetics MGG (1979)
-
Cloning and characterization of EcoRI and HindIII restriction endonuclease-generated fragments of antibiotic resistance plasmids R6-5 and R6
Molecular and General Genetics MGG (1978)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
