Abstract
ALTHOUGH the absorptive function of intestinal cells has been studied in depth, the capacity of intestinal mucosa to metabolise ingested substances has received less attention. But the gut wall presents a first line of defence against potentially harmful agents and it is likely that its detoxifying properties are important.
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References
Hartiala, K., Physiol. Rev., 53, 496–534 (1973).
Conolly, M. E., et al., Br. J. Pharmac., 46, 458–472 (1972).
Paterson, J. W., Conolly, M. E., Davies, D. S., and Dollery, C. T., Lancet, ii, 426–429 (1968).
Redwood, D., Br. med. J., 1, 26–29 (1969).
George, C. F., Blackwell, E. W., and Davies, D. S., J. Pharm. Pharmac., 26, 265–267 (1974).
Levy, G., and Matsuzawa, T., J. Pharm. exp. Ther., 156, 285–293 (1967).
Robbins, P. W., and Lipmann, F., J. biol. Chem., 229, 837–852 (1957).
Boström, H. D., Brömster, H., Nurdenstam, H., and Wengle, B., Scand. J. Gastroenterol., 3, 369–375 (1968).
Davies, D. S., in Evaluation of Bronchodilator Drugs, 151–163 (Trust for Education and Research in Therapeutics, London, 1974).
Houston, B. J., and Levy, G., Nature, 255, 78–79 (1975).
Levy, G., and Yamada, H., J. Pharm. Sci., 60, 215–221 (1971).
Speizer, F. E., Doll, R., Heaf, P., and Strang, L. B., Br. med. J., 1, 339–343 (1968).
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BENNETT, P., BLACKWELL, E. & DAVIES, D. Competition for sulphate during detoxification in the gut wall. Nature 258, 247–248 (1975). https://doi.org/10.1038/258247a0
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DOI: https://doi.org/10.1038/258247a0
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